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Follicle-Stimulating Hormone (FSH) Insensitivity

(also: E.I.S.)

Table of Contents

General Information

The body of someone with FSH insensitivity does not respond to FSH.

Someone with FSH insensitivity and XX chromosomes is usually born with a vagina, vulva, and ovaries. The ovaries may produce lower amounts of estrogen than what is typical, and may not produce fertile eggs. They may not develop secondary sex characteristics associated with a typical estrogen-based puberty and may not menstruate.

Someone with XY chromosomes and FSH insensitivity may develop smaller than typical testes, may produce fewer sperm than usual, and may not be fertile.

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